From Clinical Endocrinology News, reference to a study by Dr. Richard Zubarik that suggests hypothyroid patients taking at least 125mcg of levothyroxine, or 1.5mcg/kg/day in order to remain euthyroid, should be routinely screened for celiac disease. The results showed that 5% taking high-dose therapy were found to have biopsy-confirmed celiac disease. This is at or above the threshold of those with asymptomatic iron-deficiency anemia (2.3-5%) who have celiac disease and above the 0.75% prevalence in the U.S population. http://www.clinicalendocrinologynews.com/home/article/think-celiac-disease-in-patients-requiring-high-dose-levothyroxine/68dbf81fbf90ace4febf7d1a8704ca9a.html
Those taking high-dose levothyroxine to successfully manage hypothyroidism may benefit from screening for celiac disease, a potentially life-altering disease.