Hansten and Horn dot com: http://www.hanstenandhorn.com/news.htm This website is written by the original experts, those that I can recall as the experts back when I was in pharmacy school, and let’s not go back to when that was. I went there based on a link in U.S. Pharmacist and their article referring to a study on physician response to the drug interaction alert for hyperkalemia from interacting drugs, such as ACE inhibitors and potassium-sparing diuretics. The study takes the drug interaction to a more significant level for the practitioner showing that hyperkalemia is less likely to occur in those with low-normal or normal serum potassium levels as compared to those with high-normal levels, suggesting underlying risk factors such as renal dysfunction, etc. are significant contributing factors to hyperkalemia. The article also shows a lack of intervention from physicians based on the high-risk alert coming up in their CPOE software. It is suggested that software can be better tailored to take into account those patients at high-risk so the alert comes up for those more likely to experience this interaction versus those in whom it is not likely to occur. Their site has very good content for those interested in study how adverse drug events are caused by drug-drug interactions.