The FDA released a communication November 19, 2010 which notified health professionals and the public that they were removing propoxyphene (Darvon and Darvocet) from the U.S. market due to recent evidence that the drug causes cardiac toxicity, even at therapeutic doses. If you are using this drug, which is a Beers List drug, meaning we always recommended its discontinuation due to risks outweighing benefits, you should talk to your physician immediately to find an alternative for pain management. Keep in mind that acetaminophen has been found equally effective as propoxyphene but without the toxic effects. Most people can take up to 1000mg or 1gm of acetaminophen four times a day. 1000mg is the equivalent to two extra strength Tylenol (acetaminophen). Below is the link to the FDA press release.